Endocrine Abstracts

Goals: The purpose of this article is to describe an educational program of lifestyle intervention rather successful, taught for 25 groups of customers of a private hospital in Amazon, for a total of 2,215 individuals between 2008 and 2014, 1448 being female and male 767 and briefly assess its results in relation to some of the main risk factors.Methods: The PVS - Programa Vida Saudável, promotes evaluations and individual and group counselling, con...

BackgroundSerum urate (SU) has been positively and independently associated with type 2 diabetes in observational studies, but causal roles remain unclear.1 Triglycerides and glucose (TyG) index can be a useful and easily performed indicator of insulin resistance for daily clinical practice.2 The aim of this study was to evaluate the association between SU and TyG index in 22-year-old participants of a birth cohort.<p class="abs...

Introduction: The prevalence of vitamin D deficiency is high, and yet still little recognized and treated. Cardiovascular diseases are the leading causes of morbidity and mortality worldwide and the emergence of evidence with the link suggesting an association between vitamin D deficiency and cardiovascular risk (CVR), it is pertinent to better understand this association.Objective: This study aimed to relate the levels of 25 (OH) D in obese patients wit...

Introduction: The pseudohypoparathyroidism (PHP) encompasses a heterogeneous group of diseases characterized by end-organ resistance to parathyroid hormone (PTH). PHB type 1b (PHP1b) presents with PTH resistance at the renal proximal tubule, sometimes with TSH resistance, usually in the absence of Albright’s hereditary osteodystrophy (AHO) clinical features.Case report: A 64-year-old male was referred to endocrinology department for hypocalcemia. He...

Introduction: Radioiodine treatment (RAIT) is an effective definitive treatment for Graves’ Disease (GD) and Toxic Nodular Goiter (TNG). The aim of this study was to analyze demographic and clinical factors affecting the outcome of RAIT in patients with hyperthyroidism.Methods: Retrospective review of patients treated with RAIT for hyperthyroidism. A fixed dose of 10 mCi was administered to patients with GD and 15 mCi to patients with TNG. Treatment...

Introduction: The incidence of glucose metabolism alterations during the follow-up of surgically treated insulinomas is largely unknown. Our aim was to evaluate the incidence, and the clinical characteristics, of diabetes and prediabetes in this population.Methods: We retrospectively analyzed the cases diagnosed as insulinomas in a Central Hospital in Portugal in the period between January 1980 and December 2015.Results: We identif...

Introduction: Obesity is a chronic disease associated with multiple comorbidities, defined by BMI, without considering the metabolic state of the patient. There are few data on the proportion of obese patients without metabolic syndrome (MS).Objective: To characterize patients considered to be metabolically healthy (MH) followed at the obesity outpatient clinic of one University Hospital, and to compare this group with a group of obese patients with MS.<...

Introduction: Insulinomas are pancreatic endocrine tumors originating in the beta cells, characterized by hypoglycemia resulting from insulin hypersecretion.Objectives: To characterize the demography, the clinical features, imagiological findings and pathological evaluation of the cases of insulinomas identified in the previous 35 years at São João Hospital.Methods: We retrospectively analyzed the cases diagnosed as insul...

Background: Diabetes is an important risk factor for major adverse cardiovascular events (MACE). Although the increased risk for MACE is well known, the impact on the in-hospital outcomes remains incompletely understood. Our aim was to evaluate the interrelation between diabetes and MACE in a central hospital in the North of Portugal between 2009 and 2015.Methods: We evaluated retrospectively the hospitalizations due to MACE including stroke or transient...

Multiple benign symmetric lipomatosis (Madelung’s disease, Launois–Bensaude syndrome) is significantly rare disease characterised by symmetrical focal deposition of adipose tissue in the neck, upper part of the arms, back, pelvis, and thigh. Although its etiology is uncertain, it has been associated with genetic factors, mitochondrial inheritance and alcoholism. Its pathogenesis seems to include a dysfunction of cAMP and levels of catecholamines in adipocytes. This c...